The data show that patients who took lorcaserin achieved greater reductions in body weight than the placebo group in all subgroups evaluated. Lorcaserin patients achieved greater improvements in total cholesterol, triglycerides, HDL cholesterol and insulin resistance compared to placebo across all subgroups. Greater improvements were also seen in fasting insulin, fasting glucose and blood pressure for lorcaserin patients compared to placebo overall and in most subgroups. Blood pressure did not increase in any evaluated subgroup.

Christen M. Anderson, M.D., Ph.D., Arena's Vice President of Clinical Development, stated, "The pooled Phase 3 data show that lorcaserin successfully treated a diverse population of adult women and men who needed to lose weight. Lorcaserin's effect on weight loss also led to improvements in cardiovascular risk factors in all subgroups evaluated."

SOURCE Arena Pharmaceuticals, Inc.