?· The researchers found no statistically significant differences between the two groups in: donor age, gender of the recipient, warm ischemia time, pre-transplant diabetes and high blood pressure and LDL and HDL cholesterol.
"TRAS should be suspected in any kidney transplant patient with severe or uncontrolled high blood pressure and/or kidney function deterioration that cannot be explained by rejection or drug nephrotoxicity" concludes Dr Heshmatzade Behzadi.
"Early diagnosis and treatment of TRAS before irreversible structure changes take place in the transplanted organ may enable clinicians to restore full blood flow with minimal risks to the patient."
"The worldwide prevalence of end-stage kidney disease is increasing and demand for transplant organs significantly exceeds supply" explains Dr Cordelia Ashwanden, the journal's editor-in-chief. "That is why it is so important to explore the pros and cons of all forms of kidney transplants, including those from living unrelated donors.
"It is estimated that about four out of ten of all kidney transplants use organs legally provided by relatives and unrelated living donors, as opposed to deceased donors, and that the practice has increased significantly over the last decade.
"This paper adds valuable information on the clinical implications of using unrelated donor kidneys when it comes to the incidence of TRAS, an important post-transplant vascular complication."
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