Among his many accomplishments, Pandolfi's prolific laboratory has characterized the function of oncoproteins and genes involved in the chromosomal translocations of APL, as well as of major tumor suppressors such as PTEN and p53, and novel proto-oncogenes, such as POKEMON. More recently, Pandolfi's laboratory challenged a central dogma of molecular biology with the discovery of a novel and critically important new role for messenger RNA that includes previously unrecognized biological functions for both coding and noncoding mRNA.

"I'm extremely honored to receive the Pezcoller award," says Pandolfi. "This is a tremendously exciting time - I would even say revolutionary - for cancer research and I'm thrilled to be a part of it. As we now clearly recognize, 'cancer' is not a single disease, but is made up of many, many different mutations. While this provides us with unprecedented opportunities for developing personalized treatments, our ultimate goal is to understand and cure cancer, and this award gives us further motivation to achieve this goal as we continue to fight relentlessly for the sake of our patients."

Source: Beth Israel Deaconess Medical Center