"This research is very exciting as alopecia areata affects a huge number of people worldwide, and there are very few treatments for it-resulting in an enormous unmet medical need," said Vicki Kalabokes, president and CEO of the National Alopecia Areata Foundation, which has funded Dr. Christiano for the past 13 consecutive years. "Hair loss creates daily life issues, especially for children who experience social stigma. It affects their quality of life and can lead to long-term psychosocial impact."

Contributing to the emotional impact of alopecia areata is the nature of the disease itself. Alopecia areata is a cyclical disease having bald patches appear and, in most cases grow back, only to appear again. In many instances, the bald patches can progress to a more extreme, yet rare, form of the disease, alopecia totalis which is total scalp hair loss or alopecia universalis, resulting in the total loss of all body hair. Included in Dr. Christiano's discovery, however, is the ability to now predict with accuracy the progression of the disease in a patient. Using the number of genes associated with disease as the marker, a genetic test has been created that can indicate the severity of disease. For the patient, this means that one will be able to determine the likelihood of their bald patch progressing to complete body hair loss.

SOURCE National Alopecia Areata Registry