With regard to the extent of the development pipeline CSO Dr. Frank Mattner stated: "Even before the start of the company's first phase II study we were able to build up a very broad product pipeline. This success is based on two components: our AFFITOME(R) technology and our solid financial basis. The AFFITOME(R) technology is increasingly proving itself to be more than an ideal platform technology for our product developments. It provides innovative solutions for the therapeutic treatment of chronic diseases with unmet medical need and opens up attractive markets for us. Our investors, the MIG Fonds, had already recognised this potential four years ago. In this way they assured us of early and substantial financing, which has contributed decisively to the rapid and successful progress of our development projects".

Strategy with Success

The first successes of this business strategy came in October 2008 when GlaxoSmithKline (GSK) Biologicals acquired the licence to the rights to the Alzheimer's vaccines in a milestone deal with a value of up to EUR 430 million. Two payments totalling EUR 32.5 million have already been triggered. AFFiRiS AG continues to hold all rights on the AFFITOME(R) technology for other indications. In summary, the AFFITOME(R) technology delivers short peptides which functionally mimic highly-specific original native structures that are the key targets for treatment of chronic diseases. Based on these peptides, vaccines can be generated which induce antibodies targeting pathological variants of human proteins, but leaving parental "healthy" structures untouched.

SOURCE AFFiRiS AG